Wound Product

Silver Sulfadiazine Cream (Flamazine)

Last Updated
19 May 2025

Quick Overview

Silver sulfadiazine (SSD) is a widely used topical antimicrobial agent in wound care, especially in burn management. Its dual mechanism of action targets bacterial growth, significantly reducing the risk of wound infections.

Maximum Wear Time

As per individual patient requirements but generally once per day and should be considered as a medication

Exudate Management

Nil

Application Orientation

Place cream over affect area

Alternatives

There are no alternative products currently associated with this product. You can submit a recommended alternative dressing to be included in future updates by clicking on the button below.

Product Information

HMIF / Ordering Code

Order through pharmacy / Vendor

Categories

Brand

Uses

  • Burns
  • Infected wounds
  • Not a first line product

Positives

  • Can be used on both open and closed wounds
  • Antimicrobial
  • A think consistency allowing reduction in pain on application as apposed to thicker ointments
  • Can be used in conjunction with other dressings

Limitations

  • The cream requires time to be absorbed other wise it can be absorbed into the secondary dressing
  • Where a secondary dressing much be used shortly after applying the cream make sure that their is a silicone interface between the cream and the dressing. The cream is too thick to pass through the pores of the silicone dressing but still allows exudate to be collected by the secondary dressing
  • Where the cream is used in large areas the absorption of the silver needs to be assessed for long term treatment plans

Precautions

  • Systemic absorption of sulfadiazine can occur, particularly in patients with extensive burns or compromised skin barriers, leading to potential adverse effects such as leukopenia, nephrotoxicity, and hypersensitivity reactions.
  •  Common side effects include:
    • Local irritation
    • Burning
    • Pruritus

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